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Mass Spectroscopy

High Resolution Mass Spectroscopy

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This technology has both large and small molecule applications. Primera has the capability to offer our HRMS services utilizing the Thermo Scientific Q Exactive Plus HRMS system with Vanquish UPLC.

The Q Exactive Plus system utilizes Hybrid Quadrupole-Orbitrap Technology allows for more-accurate quantitation of low-abundance analytes in complex matrices. Primera also utilizes Thermo Biopharma database and analysis tools for large molecule applications.

High Resolution Mass Spectroscopy HRMS orbitap
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Liquid Chromatography - Mass Spectroscopy

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Primera maintains multiple LC-MS/MS, systems include the following models: 

  • Sciex API17500 (LC-MS/MS)

  • Sciex API6500 (LC-MS/MS)-SeleXION
  • Sciex API5000 (LC-MS/MS)
  • Sciex API4000 (LC-MS/MS)
We utilize state-of-the-art instrumentation combined with highly skilled, experienced lab members to provide timely, quality service grounded in strong scientific knowledge. To speak to a Primera team member about your upcoming projects click here: Primera Service Inquiry


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  • Primera offers elemental impurity analysis through ICP-MS (Inductively Coupled Plasma Mass Spectroscopy)
  • Method development, method validation, method transfer, and routine testing are available
  • Quick screening of ~50 common elements for your sample
  • Applications: USP <232> & <233>, ICH Q3D
  • Experience with Complex Matrices
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  • 3 ICP/MS systems (Agilent 7900 and two Agilent 7700)
  • CEM Mars 5 and 6 Microwave Digestion
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